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Charis Aesthetics

Sunekos vs bio-remodelling

Amino acids versus hyaluronic acid — what each supplies, which skin each suits, and why the choice is clinical rather than a preference.

Written and clinically reviewed by Ashleigh Trickett, Registered Nurse & Aesthetic PractitionerNMC 22A2789ELast reviewed

Both improve skin quality without adding volume, both get called skin boosters, and both are marketed with near-identical language. The difference is in what they supply to the skin and therefore in which skin they suit — and it is a real difference rather than a branding one.

What bio-remodelling supplies

Stabilised hyaluronic acid, at high concentration, formulated to spread through the tissue rather than hold its shape in one place. It hydrates from within and firms, and over a short course it supports the skin's own collagen and elastin production.

The protocol is short — typically two sessions four weeks apart — which is part of its appeal. It is efficient, and for the right skin the change in bounce and glow is substantial.

What Sunekos supplies

Hyaluronic acid plus a patented blend of six amino acids — the raw materials from which the skin builds collagen and elastin. The intention is not simply to hydrate but to give the skin the components to rebuild its extracellular matrix, the structural scaffolding that holds it firm.

The protocol is longer: usually four sessions spaced one to two weeks apart, with results continuing to develop after the course. It asks more of you in appointments and time.

Which skin suits which

If your skin is dull and lacks bounce but is reasonably thick and undamaged, bio-remodelling is usually the more efficient choice — fewer appointments, quick visible improvement in hydration and firmness.

If your skin has genuinely thinned and lost density — crepey, fragile, showing fine lines at rest rather than on movement — an amino-acid-based option generally does more, because the problem is a lack of structure rather than a lack of water.

Around the eyes, where skin is thinnest, the amino-acid options and polynucleotides both tend to outperform bio-remodelling for the same reason: a spreading hyaluronic acid has less to work with in very thin tissue.

Where polynucleotides fit

Worth mentioning because they are constantly compared with both. Polynucleotides work differently again — they support the skin's own repair machinery rather than supplying either water or building blocks.

In practice the three overlap considerably and are often used in sequence rather than chosen between. Someone with thin, sun-damaged skin might have polynucleotides to improve repair, then bio-remodelling to maintain hydration.

A note on the brand names

Profhilo is the best-known bio-remodelling product but it is not the only one. We use Teoxane BabyGLOW for that role here, chosen on evidence, safety profile, manufacturing standards and how it behaves in the tissue rather than on name recognition.

If you specifically want Profhilo, say so at consultation and we will talk it through honestly — including where I think another product would serve you better, and where I think it would not matter.

How the choice is actually made

By looking at your skin, pinching it, and assessing how it behaves — not from a menu. The questions are: is this skin dehydrated or is it thin? Is the problem quality across a broad area or density in a specific one? What has been tried, and how did it respond?

That is a genuine clinical decision, and it is a reasonable use of a consultation even if you leave without booking anything.

Sources and further reading

This page is general information, not personal medical advice. Every treatment needs an individual assessment, and what is right for someone else may not be right for you.

Ashleigh Trickett in the Charis Aesthetics treatment room, in front of the clinic's certificates

About the author

Ashleigh Trickett

Registered Nurse & Aesthetic Practitioner

Registered Nurse with a BSc in Nursing and a PGCert in Critical Care (Manchester Metropolitan University, 2025). Ten years in the NHS, four of them in critical care. Advanced facial anatomy education at the Royal College of Surgeons with BAMAN, June 2026. Member of BAMAN and the Aesthetic Complications Expert Group. BAMAN Awards 2026 finalist for Rising Star of the Year.

Treatments this relates to

  • Sunekos£250

    An amino acid and hyaluronic acid injectable that supports the skin's extracellular matrix — used where skin has lost density.

  • Teoxane BabyGLOW£295

    A skin booster that improves hydration, elasticity and firmness across larger areas — face, neck and hands — without adding volume.

  • Skin BoostersFrom £140

    The category explained — what a skin booster is, how the options differ, and how to work out which one you actually need.

Common questions

Which is better, Sunekos or bio-remodelling?
Neither is universally better. Bio-remodelling suits dull, lax but reasonably thick skin and needs fewer sessions. Amino-acid options suit skin that has thinned and lost density, especially around the eyes, and need a longer course.
Can I have both?
Yes, and it is common — usually in sequence rather than at the same appointment.
How many sessions does each need?
Bio-remodelling is typically two, four weeks apart. Sunekos is typically four, one to two weeks apart. Both need maintenance.
Which is better around the eyes?
Generally the amino-acid options or polynucleotides, because the skin there is thin and needs structure rather than a spreading hydrator.
Do you use Profhilo?
We use Teoxane BabyGLOW for bio-remodelling, chosen on its evidence and behaviour in the tissue. Ask at consultation and I will explain the comparison honestly.

Get in touch

Book a consultation

Consultations are £30, and that comes off the cost of your treatment if you go ahead. No pressure to book anything on the day — if you are not sure whether you want treatment at all, that is still a good reason to come and talk.